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While National Plans commonobjective is to ensure equal access and availability of services for the prevention,diagnosis, treatment and rehabilitation to people with RD, National Authorities canchoose the speci?c measures to be dealt with in their Plan.

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This might suggest the exis-tence of a feedback loop between eIF4E, Mdm2, p53 and PML.

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The duration of actionis short: starts wearing off after 30–40 min dueto redistribution, while elimination t? is ~4 hr.In the injectable form it is almost exclusivelyused in anaesthesia (see p.

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